{"id":4272,"date":"2025-08-30T09:54:43","date_gmt":"2025-08-30T16:54:43","guid":{"rendered":"https:\/\/wrwofficial.com\/index.php\/2025\/08\/30\/biological-age-tests-should-you-get-one\/"},"modified":"2025-08-30T09:54:46","modified_gmt":"2025-08-30T16:54:46","slug":"biological-age-tests-should-you-get-one","status":"publish","type":"post","link":"https:\/\/wrwofficial.com\/index.php\/2025\/08\/30\/biological-age-tests-should-you-get-one\/","title":{"rendered":"Biological age tests: Should you get one?"},"content":{"rendered":"<p><\/p>\n<div>\n<h2>If you\u2019ve heard of billionaire Bryan Johnson, you\u2019ve likely encountered the phrase \u201cbio age testing.\u201d<\/h2>\n<p>Johnson, the subject of the Netflix documentary <em>Don\u2019t Die<\/em>, says he\u2019s on a quest to achieve the lowest possible \u201cbiological age\u201d (also known as bio age).<\/p>\n<p>He reportedly spends millions each year on anti-aging treatments\u2014dozens of daily supplements, weekly acid peels for his skin, injections to boost collagen production, hyperbaric oxygen therapy, and plasma infusions extracted from his 17-year-old son\u2019s body.<\/p>\n<p>To determine what\u2019s working, Johnson has undergone numerous tests to assess his bio age. Johnson says these tests show his age is now 5.1 years younger than when he embarked on his anti-aging quest.<\/p>\n<p>Apparently, he\u2019s aging in reverse.<\/p>\n<p>Granted, not everyone\u2019s buying it. A <em>New York Times<\/em> expos\u00e9, for example, claims Johnson\u2019s biological age, in reality, has increased by 10 years.<sup>1<\/sup><\/p>\n<p>Still, Johnson\u2019s \u201cdon\u2019t die\u201d crusade is gaining traction.<\/p>\n<p>Bio age tests are a frequent topic on popular podcasts by Peter Attia, Joe Rogan, and Andrew Huberman. Google \u201cbio age testing\u201d and you\u2019ll see dozens of ads for mail-order blood or urine testing kits that claim to reveal your biological age, pace of aging, and more. With prices tumbling into affordability, it\u2019s natural to wonder\u2026<\/p>\n<p><strong>Should you or your client sign up for bio age testing?<\/strong><\/p>\n<p>If so, which test is best? Just as importantly, what should you do with the information?<\/p>\n<p>In this story, you\u2019ll learn:<\/p>\n<h2>What is your bio age?<\/h2>\n<p><strong>Your biological age (bio age) refers to how your cells function.<\/strong> It\u2019s not necessarily the same as your chronological age, which refers to the number of candles on your birthday cake.<\/p>\n<p>For example, let\u2019s say Chang, a 50-year-old man, works at a desk, spends his free time in front of the TV, lives in the most polluted city in the world, eats a candy bar for lunch, and smokes. On the other hand, Jabari, a different 50-year-old man, hits the gym several times a week, lives in the mountains, doesn\u2019t smoke, relishes his five servings of veggies a day, meditates, and spends most evenings in his garden.<\/p>\n<p>Genetics aside, you\u2019d be wise to wager that Jabari\u2019s bio age is younger than Chang\u2019s.<\/p>\n<h2>How do these tests measure bio age?<\/h2>\n<p>Bio age testing kits measure one or more biological markers of aging, also known as <strong>biomarkers<\/strong>.<\/p>\n<p>For example, <strong>some tests focus on the size of your telomeres<\/strong>, the protective caps at the ends of chromosomes. <strong>Others measure DNA methylation<\/strong>, a physiological process that chemically alters DNA.<\/p>\n<p>Once a company isolates and measures these markers from your blood or urine, it plugs the bio data into a formula that calculates your bio age.<\/p>\n<p>However, if you see a doctor with any regularity, you\u2019re likely already tracking some biomarkers of aging. For example, biomarkers such as blood pressure, cholesterol levels, and blood glucose can help predict your risk of future cardiovascular disease, a leading cause of premature death.<\/p>\n<h2>What\u2019s the point of biomarker testing?<\/h2>\n<p>Biomarker testing can help you monitor your wellness proactively rather than waiting for disease symptoms to appear.<\/p>\n<p>For some, it also serves as a motivator. If you learn you have the bones of someone 20 years older, this may give you the nudge you need to start strength training consistently.<\/p>\n<p>In addition, biomarkers provide objective data, allowing you to track and evaluate various health-related actions quantitatively. By monitoring your blood pressure, you might learn that consistent exercise helps, but your late-afternoon energy drink does the opposite.<\/p>\n<h2 id=\"free-biomarker-tests\">5 FREE biomarker tests<\/h2>\n<p>You don\u2019t have to be a billionaire (or even a millionaire) to track biomarkers of aging.<\/p>\n<p>In this section, we\u2019ll cover several massively underappreciated, scientifically validated tests you can use to gain insight into your bio age\u2014for FREE.<\/p>\n<p>Before scientists developed high-tech blood-based bio age tests, researchers used these free tests to calculate the pace of aging in the people they studied.<\/p>\n<h3>FREE biomarker test #1: Get off the floor<\/h3>\n<p>People who are fitter and stronger tend to live longer.<sup>2<\/sup><\/p>\n<p>That\u2019s because muscles do more than just move us around. They also secrete anti-inflammatory substances, help to regulate blood sugar, slow cellular aging, protect the lining of the arteries, and more. All this helps reduce the risk of age-related diseases, such as type 2 diabetes, high blood pressure, and heart disease, a phenomenon we explore in our article, <a href=\"https:\/\/www.precisionnutrition.com\/build-muscle-strength-size-power\">The New Science of Muscle.<\/a><\/p>\n<p>Related to strength, your ability to balance is also key. If you\u2019re middle-aged or older and can\u2019t stand on one foot for at least 10 seconds, your risk of dying in the next seven years is double that of someone who can stand for longer, according to a study of 1,700 people.<sup>3<\/sup><\/p>\n<p><strong>The Sitting-Rising Test (SRT) is one way to assess both strength and balance at the same time.<\/strong><\/p>\n<p>People with low scores on this test have a higher risk of dying from cardiovascular disease, according to a 12-year study of 4,200 adults between the ages of 46 and 75.<sup>4<\/sup><\/p>\n<p><strong>\u25b6 How to measure it<\/strong><\/p>\n<p>Lower yourself to the floor with your legs in a crisscross position. Then, with your legs in the same position, stand back up. As you stand, notice if you must use a part of your body\u2014hand, shin, knee\u2014as leverage.<\/p>\n<p>To score yourself, start with 10 points. Then, for each body part you used to stand, deduct a point. Subtract a half point if you became unsteady or lost your balance.<\/p>\n<p>Keep in mind that this (and other tests) serve as a <em>proxy<\/em> for your fitness. A low score indicates that your balance and coordination, muscle strength and power, and mobility may all require some attention.<\/p>\n<h3>FREE biomarker test #2: Squeeze a ball<\/h3>\n<p>Like the SRT test, your grip strength provides insight into your overall fitness. If the muscles in your hands are weak, the muscles throughout your body are more likely to be weak, too.<\/p>\n<p>Poor grip strength can also predict <em>future<\/em> muscle weakness. In one study, people with a weak grip were more likely to walk slowly and be unable to rise from a chair, complete rigorous housework, or climb a flight of steps 25 years later.<sup>5<\/sup><\/p>\n<p>Low grip strength has also been associated with:<sup>6<\/sup><\/p>\n<ul class=\"pn-list__spaced\">\n<li>Low bone mineral density<\/li>\n<li>Increased risk of falls<\/li>\n<li>Poor nutritional status<\/li>\n<li>Depression<\/li>\n<li>Poor sleep, cognitive function, and\/or quality of life<\/li>\n<li>Increased risk of heart disease, cancer, and premature mortality<\/li>\n<\/ul>\n<p>According to one study, grip strength was a better indicator of longevity (or lack thereof) than blood pressure.<sup>7<\/sup><\/p>\n<p><strong>\u25b6 How to measure it<\/strong><\/p>\n<p>Grab a standard tennis ball, and squeeze as hard as you can, for as long as you can.<\/p>\n<p>If you can manage 15 to 30 seconds before your grip fatigues, you\u2019re doing fine. Ninety seconds puts you well above average\u2014anything over 90 ranks you solidly in the upper-third percentile.<\/p>\n<p>If you\u2019re below 15, keep in mind that this test is also just one indicator of your overall strength. (And squeezing balls to improve grip strength without training the rest of your body is unlikely to make significant improvements in your overall health and fitness.)<\/p>\n<p>A hand-held dynamometer\u2014available for use at most occupational therapists\u2019 and some gyms\u2014can also test grip strength. (If you\u2019re willing to shell out some cash, you can buy your own for somewhere between $100 and $500.)<\/p>\n<h3>FREE biomarker test #3: Stand on one foot<\/h3>\n<p>An ability to balance on one foot for an extended period can help reduce your risk of falls, one of the leading causes of injury-related death among older adults.<\/p>\n<p>In addition, many different bodily systems\u2014the eyes, inner ear, skeletal muscles, and brain\u2014must work together to help you stay upright.<\/p>\n<p>Conditions like diabetes, heart disease, and cancer can all affect balance. As a result, an inability to stand on one foot can serve as a warning sign for eroding health and fitness.<sup>8<\/sup><\/p>\n<p><strong>\u25b6 How to measure it<\/strong><\/p>\n<p>Stand near a wall or chair for safety. Keep your eyes open and hands on your hips. Then, lift your dominant leg and start timing yourself. Once you put your foot down, stop the clock. Repeat the test with your non-dominant leg.<\/p>\n<p>Once you have your times, compare them to the following averages, from a study out of Duke University, to see how you did compared to your age-matched peers.<sup>9<\/sup><\/p>\n<table style=\"width: 100%;\">\n<thead>\n<tr>\n<th style=\"width: 33%;\"><strong>Age<\/strong><\/th>\n<th style=\"width: 33%;\"><strong>Seconds on one leg (males)<\/strong><\/th>\n<th style=\"width: 34%;\"><strong>Seconds on one leg (females)<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>30-39<\/td>\n<td>59<\/td>\n<td>56<\/td>\n<\/tr>\n<tr>\n<td>40-49<\/td>\n<td>56<\/td>\n<td>55<\/td>\n<\/tr>\n<tr>\n<td>50-59<\/td>\n<td>42<\/td>\n<td>48<\/td>\n<\/tr>\n<tr>\n<td>60-69<\/td>\n<td>40<\/td>\n<td>38<\/td>\n<\/tr>\n<tr>\n<td>70-79<\/td>\n<td>27<\/td>\n<td>25<\/td>\n<\/tr>\n<tr>\n<td>80+<\/td>\n<td>13<\/td>\n<td>11<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>FREE biomarker test #4: How you feel<\/h3>\n<p>Sometimes you know why you\u2019re tired, such as the morning after binge-watching the last few episodes of a thriller. Once you catch up on your sleep, the weariness lifts.<\/p>\n<p>That\u2019s not the same thing as <em>fatigue<\/em>, which describes persistent exhaustion that worsens over time and interferes with life. In addition to feeling physically tired, someone who\u2019s fatigued feels mentally dull and emotionally exhausted.<\/p>\n<p><strong>Think of fatigue as an early sign that something\u2019s off, especially if you don\u2019t know the cause.<\/strong><\/p>\n<p>Let\u2019s say you\u2019ve already ruled out the usual suspects like too much caffeine, dehydration, too much alcohol, medication side effects, chronic stress, or too much or too little exercise. What\u2019s left is likely a sleep disorder or a developing health problem such as anemia, obesity, depression, cancer, or diabetes, to name a few.<\/p>\n<p>If you\u2019re 60 or older, <em>fatiguability<\/em>\u2014or how worn out you feel after an activity\u2014can also predict longevity.<\/p>\n<p>According to research out of the University of Pittsburgh Medical Center, the higher someone scores in fatiguability, the higher their risk of death in the future.<sup>10<\/sup> Other research has linked high fatiguability with declines in gait speed, walking ability, and other tests of fitness.<sup>11<\/sup><\/p>\n<p><strong>\u25b6 How to measure it<\/strong><\/p>\n<p>To measure fatigability, use a tool called the Pittsburgh Fatigability Scale. Using a 0 (no fatigue) to 5 (extreme fatigue) scale, rate how fatigued you think you would feel after completing the following activities:<\/p>\n<table>\n<thead>\n<tr>\n<th><strong>Activity<\/strong><\/th>\n<th><strong>Duration<\/strong><\/th>\n<th><strong>Score (0 to 5)<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Leisurely walking<\/td>\n<td>30 minutes<\/td>\n<td\/>\n<\/tr>\n<tr>\n<td>Brisk or fast walking<\/td>\n<td>1 hour<\/td>\n<td\/>\n<\/tr>\n<tr>\n<td>Light household activity<\/td>\n<td>1 hour<\/td>\n<td\/>\n<\/tr>\n<tr>\n<td>Heavy gardening or yard work<\/td>\n<td>1 hour<\/td>\n<td\/>\n<\/tr>\n<tr>\n<td>Watching television<\/td>\n<td>2 hours<\/td>\n<td\/>\n<\/tr>\n<tr>\n<td>Sitting quietly<\/td>\n<td>1 hour<\/td>\n<td\/>\n<\/tr>\n<tr>\n<td>Moderate-to-high intensity strength training<\/td>\n<td>30 minutes<\/td>\n<td\/>\n<\/tr>\n<tr>\n<td>Participating in a social activity<\/td>\n<td>1 hour<\/td>\n<td\/>\n<\/tr>\n<tr>\n<td>Hosting a social event for 60 minutes<\/td>\n<td>1 hour<\/td>\n<td\/>\n<\/tr>\n<tr>\n<td>High intensity activity<\/td>\n<td>30 minutes<\/td>\n<td\/>\n<\/tr>\n<tr>\n<td colspan=\"2\"><strong>Add all scores:<\/strong><\/td>\n<td\/>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>If you score less than 15, you\u2019re doing well. Scores between 15 and 24 are a warning sign. Anything 25 and above is regarded as severe, and worth mentioning to your healthcare professional.<sup>12<\/sup><\/p>\n<h3>FREE biomarker test #5: Body composition<\/h3>\n<p>Despite popular belief, both too little and too much body fat can influence health for the worse, as we explore in our infographic, <a href=\"https:\/\/www.precisionnutrition.com\/is-body-fat-good-or-bad\">Is body fat good or bad for you?<\/a><\/p>\n<table>\n<thead>\n<tr>\n<th><strong>Too much fat raises the risk for:<\/strong><\/th>\n<th><strong>Too little muscle raises risk for:<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Heart disease<\/td>\n<td>Heart disease<\/td>\n<\/tr>\n<tr>\n<td>High blood pressure<\/td>\n<td>High blood pressure<\/td>\n<\/tr>\n<tr>\n<td>Cancer<\/td>\n<td>Cancer<\/td>\n<\/tr>\n<tr>\n<td>Fatty liver disease<\/td>\n<td>Stroke<\/td>\n<\/tr>\n<tr>\n<td>Insulin resistance<\/td>\n<td>Insulin resistance<\/td>\n<\/tr>\n<tr>\n<td>Type 2 diabetes<\/td>\n<td>Faster cellular aging<\/td>\n<\/tr>\n<tr>\n<td>Inflammation<\/td>\n<td>Inflammation<\/td>\n<\/tr>\n<tr>\n<td>Joint distress<\/td>\n<td>Depression and anxiety<\/td>\n<\/tr>\n<tr>\n<td>Sleep apnea<\/td>\n<td>Falls and loss of balance<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Your muscle mass also plays a role, which is why someone\u2019s body <em>composition<\/em> matters more than their <em>weight<\/em>.<\/strong><\/p>\n<p>The gold standard methods that estimate body composition\u2014underwater weighing, air displacement (Bod Pod), and dual-energy X-ray absorptiometry (DEXA)\u2014certainly aren\u2019t free.<\/p>\n<p>However, a recent study determined that a good old-fashioned (and cheap) tape measure can provide a comparably accurate estimate of body composition.<sup>13<\/sup><\/p>\n<p><strong>\u25b6 How to measure it<\/strong><\/p>\n<p>To use a tape measure to keep track of your body fat percentage, measure:<\/p>\n<ul class=\"pn-list__spaced\">\n<li>The widest part of your neck<\/li>\n<li>The narrowest part of your waist (For some people, this will be at the navel. For others, it might be slightly above the navel)<\/li>\n<li>The widest part of your hips<\/li>\n<\/ul>\n<p>Ensure the tape is snug but not so tight that it cuts into the skin. Once you have your measurements, plug those numbers\u2014along with your age, sex, height, and weight\u2014into our <a href=\"https:\/\/www.precisionnutrition.com\/body-fat-calculator\">FREE Body Fat Calculator<\/a>, which will take it from there.<\/p>\n<h2 id=\"doctor-approved-biomarker-tests\">Doctor-approved biomarker tests<\/h2>\n<p>Depending on where you live in the world, the following tests may not be free. However, as part of routine preventative care, your insurance might cover them.<\/p>\n<h3>Doctor-approved test #1: Blood panel<\/h3>\n<p>If your primary care doctor recommends yearly blood work, it\u2019s for good reason.<\/p>\n<p>By keeping tabs on several blood markers, you can see if your health is trending toward type 2 diabetes or heart disease, both leading causes of premature mortality.<\/p>\n<p>Many blood markers can also be influenced relatively quickly (within 6 to 12 weeks) through lifestyle changes, supplement protocols, or medications. This makes them practical tools for monitoring whether various lifestyle or medical modifications are working.<\/p>\n<p><strong>\u25b6 How to measure it<\/strong><\/p>\n<p>If you\u2019re not already doing so, consider having the following blood markers tested annually. Then, talk to your health care professional about what your numbers mean. They might use the following numbers, along with your blood pressure, to calculate a cardiovascular disease risk score.<\/p>\n<table>\n<thead>\n<tr>\n<th><strong>Blood marker<\/strong><\/th>\n<th><strong>Optimal range<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Total cholesterol<\/td>\n<td>&lt; 200 mg\/dL*<\/td>\n<\/tr>\n<tr>\n<td>LDL<\/td>\n<td>&lt; 100 mg\/dL for those without heart disease<br \/>&lt; 70 mg\/dL for those with a history of heart attack or stroke<\/td>\n<\/tr>\n<tr>\n<td>HDL<\/td>\n<td>&gt; 60 mg\/dL<\/td>\n<\/tr>\n<tr>\n<td>Triglycerides<\/td>\n<td>&lt; 150 mg\/dL<\/td>\n<\/tr>\n<tr>\n<td>Alipoprotein B (Apo B)<\/td>\n<td>&lt; 133 mg\/dL (males)<br \/>&lt; 117 mg\/dL (females)<\/td>\n<\/tr>\n<tr>\n<td>Lipoprotein (a)<\/td>\n<td>&lt; 30 mg\/dL<\/td>\n<\/tr>\n<tr>\n<td>C-reactive protein<\/td>\n<td>&lt; 2.0 mg\/L**<\/td>\n<\/tr>\n<tr>\n<td>Fasting glucose<\/td>\n<td>&lt; 100 mg\/dL<\/td>\n<\/tr>\n<tr>\n<td>Hemoglobin A1C<\/td>\n<td>&lt; 5.7%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p class=\"pn-wysiwyg--smaller\">*Milligrams per deciliter of blood<br \/>**Milligrams per liter<\/p>\n<h3>Doctor-approved test #2: Bone density<\/h3>\n<p>When researchers study healthy super-agers aged 90 and older, strong bones are one of their defining features.<sup>14<\/sup><\/p>\n<p>That may be because, like muscles, bones are live organs that secrete substances that may be beneficial to overall health and longevity.<sup>15<\/sup><\/p>\n<p>For example, bones secrete <strong>osteocalcin<\/strong>, a hormone that plays a role in bone remodeling. When osteocalcin circulates in the body, it\u2019s thought to play a role in everything from helping muscles to produce ATP to regulating brain neurotransmitters.<\/p>\n<p>Because of these varied roles, it\u2019s thought that, as bones wear away, osteocalcin levels drop, contributing to many age-related health problems, including diabetes, low muscle mass, and cognitive issues.<sup>16<\/sup> <sup>17<\/sup> (At least, that\u2019s the theory. Most of this research has been done on mice.)<\/p>\n<p>Osteocalcin aside, loss of bone density can, of course, lead to fractures, which can increase your risk of death for up to 10 years after a break.<sup>18<\/sup><\/p>\n<p>It\u2019s especially important to keep tabs on bone health if you\u2019re in any of these high-risk categories:<\/p>\n<ul class=\"pn-list__spaced\">\n<li>You\u2019re female and went through menopause before age 45.<\/li>\n<li>You\u2019ve been sedentary most of your adult life.<\/li>\n<li>You take medications such as diuretics or stomach-acid blockers, which are linked with an increased risk of osteoporosis.<\/li>\n<li>You have a history of nicotine use or excessive alcohol consumption.<\/li>\n<li>You have a medical condition, such as diabetes or thyroid disease, that raises your risk.<\/li>\n<li>You have a family history of osteoporosis.<\/li>\n<\/ul>\n<p><strong>\u25b6 How to measure it<\/strong><\/p>\n<p>Dual-energy X-ray absorptiometry (DEXA) scans are a type of X-ray that measures the amount of bone mineral content packed into a square centimeter of bone.<\/p>\n<p>Insurance often won\u2019t cover these scans for people younger than 65 unless there\u2019s a documented risk of developing osteoporosis. Out of pocket, the average cost is about $300.<\/p>\n<p>When you receive your DEXA results, you\u2019ll see a T-score that represents how your bone density compares to the average bone density of a young adult with peak bone mass. A T-score of +1.0 to -1.0 means you have normal bone mineral density for someone your age. Anything below -1.0 means you might have osteopenia (low bone mineral density) or osteoporosis (porous bones that are prone to fracture).<\/p>\n<h2 id=\"commercial-bio-age-tests\">Commercial bio age tests<\/h2>\n<p>If you have some money to burn, you can learn an awful lot about your body.<\/p>\n<p>Here, you\u2019ll find a quick run-down on some of the more high-tech tests you can get and what they can tell you.<\/p>\n<p>However, before we get into the details, we want to point out a few caveats:<\/p>\n<p><strong>\u25b6 Biological age can vary over time, and by organ.<\/strong> Someone may go through a period of accelerated aging\u2014saying, during a period of intense stress\u2014then their rate of aging may slow as they focus more on recovery. Additionally, organs can age at different rates. For example, someone with heart disease may have a relatively older heart than their kidneys. (Not all tests measure individual organ age, but it\u2019s becoming more common.)<\/p>\n<p><strong>\u25b6 Commercial tests won\u2019t always accurately reflect the changes you\u2019re making.<\/strong> Until more research supports the reliability of these tests, evaluate your behaviors over isolated test results. If you\u2019re eating more fruits and veggies, exercising more consistently, managing stress, and otherwise slaying the healthy lifestyle department, don\u2019t sweat your results. Focus on doing the things we know improve health.<\/p>\n<p><strong>\u25b6 If a company pairs your test results with a hard sell for a proprietary and expensive supplement protocol, be wary.<\/strong> It\u2019s better to share and discuss your results with a trusted health professional than take health advice from a profit-seeking stranger over the internet.<\/p>\n<h3>Commercial test #1: DNA methylation<\/h3>\n<p>DNA methylation is a biological process that chemically alters DNA. Because the rate of methylation accelerates with aging, it can be used to estimate someone\u2019s biological age and life expectancy, finds research.<sup>19<\/sup> <sup>20<\/sup> <sup>21<\/sup><\/p>\n<p>The <strong>Horvath Clock<\/strong> and <strong>DunedinPACE<\/strong> both measure specific biomarkers that can be used to better understand someone\u2019s methylation rate. Scientists developed these tests to help other scientists study how various lifestyle factors, environmental exposures, and medicines affect aging. They didn\u2019t develop the tests as a way for the average person to pinpoint their biological age. (Which hasn\u2019t stopped companies from selling DNA methylation testing kits to the public.) They cost about $300.<\/p>\n<p>If you decide to get one of these tests, keep in mind your results won\u2019t give you a complete picture of your health and longevity. Aging typically occurs at varying rates throughout the body. Your liver might age faster than your heart or brain, for example. So if you measure DNA methylation in your blood, that\u2019s all you know about. Put another way, <strong>a DNA methylation test isn\u2019t a substitute for your annual wellness checkup or blood work.<\/strong><\/p>\n<h3>Commercial test #2: Telomere analysis<\/h3>\n<p>Telomeres\u2014the protective caps on the ends of chromosomes\u2014wear away with age. The length of a telomere can predict how many times a specific cell can divide before dying.<\/p>\n<p>Abnormally short telomeres are associated with several genetic diseases. For this reason, when physicians suspect someone might have inherited a genetic disease, they\u2019ll order a specific type of telomere test\u2014the <strong>flow-FISH test<\/strong>\u2014to measure the telomere length in all the cells in a blood sample.<sup>22<\/sup> <sup>23<\/sup><\/p>\n<p>It\u2019s more debatable whether telomere tests can predict aging in healthy people.<\/p>\n<p>Just as importantly, the telomere test marketed to the public, known as the <strong>qPCR telomere test<\/strong>, isn\u2019t used in research or medicine. These $100 tests are fine if you\u2019re merely curious\u2014just don\u2019t base health and fitness decisions on your results.<\/p>\n<h3>Commercial test #3: VO2 Max<\/h3>\n<p>For years, only elite athletes cared about VO2 max, which describes the maximum amount of oxygen that your body can use during exercise.<\/p>\n<p>More recently, however, some experts have suggested that VO2 max can serve as a measure for athletes and non-athletes alike to track the rate at which their bodies are aging.<\/p>\n<p>People with high VO2 max tend not only to be more physically fit but also less likely to develop heart disease, diabetes, cancer, or stroke.<sup>24<\/sup> <sup>25<\/sup> <sup>26<\/sup> <sup>27<\/sup><\/p>\n<p>In an observational study that followed the health outcomes of 5,107 Danish men over 46 years, men with above-average V02 max during middle age lived an average of five years longer than men with below-average V02 max. Each unit increase in VO2 max was associated with a 45-day increase in longevity. The researchers suggested VO2 max may more accurately predict all-cause mortality than high cholesterol, obesity, high blood pressure, and insulin resistance.<sup>28<\/sup><\/p>\n<p><strong>You might think of V02 max as a canary and your aging body as a coal mine.<\/strong><\/p>\n<p>As you age, your chest wall becomes more rigid, the muscles that surround the lungs weaker, and the oxygen-carrying blood vessels calcified and less elastic. The heart also squeezes with less force, max heart rate drops, muscle mass and strength decline, the mitochondria in cells and muscles lose their effectiveness, among other differences.<\/p>\n<p>In addition to raising your risk for many different diseases, these changes can also affect VO2 max, which tends to decline 10 percent per decade starting around age 30.<sup>29<\/sup> <sup>30<\/sup><\/p>\n<p><strong>In the past, the only way to reliably measure VO2 max was in a fitness lab.<\/strong><\/p>\n<p>You would wear a metabolic mask and a heart monitor while you ran or cycled to exhaustion. The mask collected your expired carbon dioxide and monitored how much oxygen you sucked into your lungs. This lab-based testing is still the most accurate way to measure V02 max as well as other key fitness metrics such as:<\/p>\n<ul class=\"pn-list__spaced\">\n<li><strong>Max heart rate<\/strong>, or the highest number of times your heart can beat per minute during exercise<\/li>\n<li><strong>Ventilatory threshold 1<\/strong>, or the point during exercise when the body switches from mainly using fat for fuel to using a combination of fat and glucose or glycogen (stored glucose) for fuel.<\/li>\n<li><strong>Ventilatory threshold 2<\/strong>, or the point where your body moves away from aerobic metabolism (which uses oxygen) to anaerobic metabolism (which doesn\u2019t use oxygen).<\/li>\n<li><strong>Tidal volume<\/strong> is the amount of air inhaled or exhaled during each breath<\/li>\n<\/ul>\n<p>Depending on where you live, you might be able to get your VO2 max tested for around $150.<\/p>\n<p>However, if you don\u2019t have access to a VO2 max clinic, three somewhat less accurate options exist.<\/p>\n<p><strong>\u25b6 The 1-mile walk test<\/strong><\/p>\n<p>Wear a heart rate monitor as you walk one mile on a flat surface, such as a treadmill or running track. As soon as you complete the mile, record your heart rate and walk time. Then, plug it into the following formula to calculate your VO2 max:<\/p>\n<p>132.853 \u2014 (0.0769 \u00d7 Weight) \u2014 (0.3877 \u00d7 Age) + (6.315 \u00d7 Sex) \u2014 (3.2649 \u00d7 Time) \u2014 (0.1565 \u00d7 Heart rate)<\/p>\n<p>If that feels like too much math, you can also use <a href=\"https:\/\/www.omnicalculator.com\/sports\/vo2-max\">a free online tool<\/a>.<\/p>\n<p><strong>\u25b6 The smartwatch test<\/strong><\/p>\n<p>Many smartwatches will estimate your VO2 Max for you based on information the watch gathers from your workouts, sex, and age. Compared to in-office testing, smart watches can over- or underestimate V02 max, especially in people who are very out of shape or extremely fit.<sup>31<\/sup><\/p>\n<p>Because of this, you don\u2019t necessarily want to use your smart watch measurement to determine your current state of health. However, it <em>can<\/em> help you to see trends. For example, does your VO2 estimate drop after a few weeks of skipping your usual spin class? If so, that\u2019s good information to have.<\/p>\n<p><strong>\u25b6 The PR test<\/strong><\/p>\n<p>Fitness performance correlates with longevity. If you\u2019re getting faster at running a certain distance or can go a longer distance than before, you\u2019re getting fitter and increasing your chances of living a long, healthy life.<\/p>\n<p>One way to test this: the 12-minute run test, also known as <strong>the Cooper test.<\/strong> (This is a validated way to estimate VO2 max\u2014and shows about a 90 percent correlation with lab-based measurements.)<\/p>\n<p>Here\u2019s how it works:<\/p>\n<p>Run as fast as you can on a flat surface, such as a treadmill set at a 1 percent incline or running track, for 12 minutes. After 12 minutes, record your distance. Then, plug it into one of the following formulas to calculate your VO2 max.<\/p>\n<table>\n<thead>\n<tr>\n<th\/>\n<th><strong>Distance in Miles<\/strong><\/th>\n<th><strong>Distance in Kilometers<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>VO2 Max =<\/strong><\/td>\n<td>(35.97 x distance in miles) \u2013 11.29<\/td>\n<td>(22.351 x distance in kilometers) \u2013 11.288<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>In lieu of doing math, you can also use a <a href=\"https:\/\/exrx.net\/Calculators\/MinuteRun\">free online calculator<\/a>.<\/p>\n<h2 id=\"how-to-change-your-biological-age\">How to change your biological age<\/h2>\n<p>Try to think of the information you gather about your body as just that\u2014information.<\/p>\n<p>It\u2019s not a moral judgment of who you are as a person.<\/p>\n<p>Just as importantly, it\u2019s not a permanent situation.<\/p>\n<ul class=\"pn-list__spaced\">\n<li><strong>If you\u2019re weaker than other people your age<\/strong>, you can grow stronger.<\/li>\n<li><strong>If your cholesterol or blood glucose levels are high,<\/strong> you can take steps to lower them.<\/li>\n<li><strong>If your body is aging faster than your birthdays<\/strong>, consider exploring key lifestyle changes that may help turn the situation around.<\/li>\n<\/ul>\n<p>You have options. However, most people make two big mistakes when it comes to longevity-related lifestyle changes.<\/p>\n<h3>Mistake #1: Ignoring evergreen, big-impact strategies<\/h3>\n<p>It\u2019s the simple, boring, \u201cI\u2019ve heard this a million times before\u201d health practices that, when done consistently, add up to a long, healthy life.<\/p>\n<p>We\u2019re talking about things like\u2026<\/p>\n<ul class=\"pn-list__spaced\">\n<li>Eating more minimally processed foods and fewer ultra-processed foods<\/li>\n<li>Consuming more brightly colored fruits and veggies<\/li>\n<li>Moving your body regularly<\/li>\n<li>Getting enough rest and sleep<\/li>\n<li>Enjoying community, time in nature, and other activities that make life meaningful<\/li>\n<li>Keeping alcohol intake moderate<\/li>\n<li>Not using tobacco<\/li>\n<li>Wearing sunscreen<\/li>\n<li>Flossing<\/li>\n<\/ul>\n<p>And that\u2019s just a partial list.<\/p>\n<p>According to thousands of studies, <strong>people who practice these and other high-impact strategies not only live longer, but also live <em>better.<\/em><\/strong> They\u2019re stronger, happier, and less likely to spend their later years disabled or in pain.<\/p>\n<p>(If you\u2019d like to see where you stand when it comes to big impact health and longevity strategies, check out our <a href=\"https:\/\/www.precisionnutrition.com\/longevity-assessment\">FREE Longevity Assessment<\/a>.)<\/p>\n<p>However, when it comes to health, fitness, and longevity, <strong>many people pursue options with minimal impact (at best).<\/strong> They reach for the latest, trendy supplement rather than taking steps to quit smoking, as just one example.<\/p>\n<p>Here\u2019s the thing: Big rock strategies require changes in behavior. If daily physical activity were as easy as popping a pill, walkers and cyclists would clog up the streets in your neighborhood.<\/p>\n<p>(It\u2019s precisely this reason why so many people need the support of <a href=\"https:\/\/www.precisionnutrition.com\/1-to-1-coaching-offer\/\">a certified health coach<\/a> who has undergone training in the science of behavior change.)<\/p>\n<h3>Mistake #2: Not turning data into action<\/h3>\n<p>The data gathered from biomarker aging tests can give you a sense of control.<\/p>\n<p>However\u2026<\/p>\n<p><strong>Data, in isolation, doesn\u2019t lead to a longer life.<\/strong><\/p>\n<p>Gathering data without changing your behavior is like checking your reflection in the mirror, seeing spinach wedged between your incisors, and leaving it there.<\/p>\n<p>You need to remove the spinach for the mirror check to be worthwhile.<\/p>\n<p>Biomarker testing is the same.<\/p>\n<p><strong>If you don\u2019t use your bio data to inform behavior change, you\u2019re wasting your money and time.<\/strong><\/p>\n<p>Consider your biomarker data as a baseline or starting point.<\/p>\n<p>Then, use it to assess whether various lifestyle changes or medical interventions are moving you closer to your goal of living a longer, healthier life.<\/p>\n<h2>References<\/h2>\n<p><a id=\"references_link\" style=\"cursor:pointer\">Click here to view the information sources referenced in this article.<\/a><\/p>\n<div id=\"references_holder\" style=\"display:none\">\n<p>1. 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Cai L, Gonzales T, Wheeler E, Kerrison ND, Day FR, Langenberg C, et al. <a href=\"https:\/\/www.nature.com\/articles\/s41467-023-38234-w\" target=\"_blank\" rel=\"noopener\">Causal associations between cardiorespiratory fitness and type 2 diabetes.<\/a> Nat Commun. 2023 Jul 3;14(1):3904.<\/p>\n<p>26. Aker A, Saliba W, Bahouth F, Naoum I, Zafrir B. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10672313\/\" target=\"_blank\" rel=\"noopener\">Cardiorespiratory fitness and risk of cardiovascular events and mortality in middle age patients without known cardiovascular disease.<\/a> J Clin Med. 2023 Nov 9;12(22):7011.<\/p>\n<p>27. Prestgaard E, Mariampillai J, Engeseth K, Erikssen J, Bodeg\u00e5rd J, Liest\u00f8l K, et al. <a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/STROKEAHA.118.021798\" target=\"_blank\" rel=\"noopener\">Change in cardiorespiratory fitness and risk of stroke and death: Long-term follow-up of healthy middle-aged men: Long-term follow-up of healthy middle-aged men.<\/a> Stroke. 2019 Jan;50(1):155\u201361.<\/p>\n<p>28. Clausen JSR, Marott JL, Holtermann A, Gyntelberg F, Jensen MT. <a href=\"https:\/\/www.jacc.org\/doi\/10.1016\/j.jacc.2018.06.045\" target=\"_blank\" rel=\"noopener\">Midlife cardiorespiratory fitness and the long-term risk of mortality: 46 years of follow-up.<\/a> J Am Coll Cardiol. 2018 Aug 28;72(9):987\u201395.<\/p>\n<p>29. Kim C-H, Wheatley CM, Behnia M, Johnson BD. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4968829\/\" target=\"_blank\" rel=\"noopener\">The effect of aging on relationships between lean body mass and VO2max in rowers.<\/a> PLoS One. 2016 Aug 1;11(8):e0160275.<\/p>\n<p>30. Strasser B, Burtscher M. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29293447\/\" target=\"_blank\" rel=\"noopener\">Survival of the fittest: VO2max, a key predictor of longevity?<\/a> Front Biosci (Landmark Ed). 2018 Mar 1;23(8):1505\u201316.<\/p>\n<p>31. Caserman P, Yum S, G\u00f6bel S, Reif A, Matura S. <a href=\"https:\/\/biomedeng.jmir.org\/2024\/1\/e59459\" target=\"_blank\" rel=\"noopener\">Assessing the accuracy of smartwatch-based estimation of maximum oxygen uptake using the Apple Watch Series 7: Validation study<\/a>. JMIR Biomed Eng. 2024 Jul 31;9(1):e59459.<\/p>\n<\/div>\n<h2>If you\u2019re a health and fitness pro\u2026<\/h2>\n<p>&#13;<br \/>\n  <strong>When your clients are stressed and exhausted, everything else becomes a&#13;<br \/>\n    struggle<\/strong>: going to the gym, choosing healthy foods, and managing cravings.&#13;\n<\/p>\n<p>&#13;<br \/>\n  But with the <strong>right tools<\/strong>, you can help your clients overcome&#13;<br \/>\n  obstacles like chronic stress and poor sleep\u2014leading them toward the&#13;<br \/>\n  <strong>lasting health transformations<\/strong> they\u2019ve always wanted.&#13;\n<\/p>\n<p>&#13;<br \/>\n  <strong><a href=\"https:\/\/www.precisionnutrition.com\/sleep-stress-management-recovery-certification-level-1-waitlist\">PN\u2019s Level 1 Sleep, Stress Management, and Recovery (SSR) Coaching&#13;<br \/>\n      Certification<\/a><\/strong>&#13;<br \/>\n  will give you these tools. And it\u2019ll give you confidence and credibility as a&#13;<br \/>\n  specialized coach who can<strong>&#13;<br \/>\n    solve the biggest problems blocking any clients\u2019 progress. <\/strong>(You can&#13;<br \/>\n  <a href=\"https:\/\/www.precisionnutrition.com\/sleep-stress-management-recovery-certification-level-1-waitlist\">join the SSR Early Access List<\/a> for our biggest discount + exclusive perks.)&#13;\n<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>If you\u2019ve heard of billionaire Bryan Johnson, you\u2019ve likely encountered the phrase \u201cbio age testing.\u201d Johnson, the subject of the Netflix documentary Don\u2019t Die, says he\u2019s on a quest to achieve the lowest possible \u201cbiological age\u201d (also known as bio age). He reportedly spends millions each year on anti-aging treatments\u2014dozens of daily supplements, weekly acid [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4273,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[327],"tags":[776,1131,773],"class_list":{"0":"post-4272","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-age","9":"tag-biological","10":"tag-tests"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.0 (Yoast SEO v26.0) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Biological age tests: Should you get one? - Well Rooted Wellness<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/wrwofficial.com\/index.php\/2025\/08\/30\/biological-age-tests-should-you-get-one\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Biological age tests: Should you get one?\" \/>\n<meta property=\"og:description\" content=\"If you\u2019ve heard of billionaire Bryan Johnson, you\u2019ve likely encountered the phrase \u201cbio age testing.\u201d Johnson, the subject of the Netflix documentary Don\u2019t Die, says he\u2019s on a quest to achieve the lowest possible \u201cbiological age\u201d (also known as bio age). 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