{"id":4864,"date":"2025-10-23T13:18:15","date_gmt":"2025-10-23T20:18:15","guid":{"rendered":"https:\/\/wrwofficial.com\/index.php\/2025\/10\/23\/antidepressant-side-effects-vary-depending-on-the-drug-shots\/"},"modified":"2025-10-23T13:18:21","modified_gmt":"2025-10-23T20:18:21","slug":"antidepressant-side-effects-vary-depending-on-the-drug-shots","status":"publish","type":"post","link":"https:\/\/wrwofficial.com\/index.php\/2025\/10\/23\/antidepressant-side-effects-vary-depending-on-the-drug-shots\/","title":{"rendered":"Antidepressant side effects vary depending on the drug : Shots"},"content":{"rendered":"<p><\/p>\n<div id=\"storytext\">\n<div id=\"resg-s1-94549\" class=\"bucketwrap image large\">\n<div class=\"imagewrap has-source-dimensions\" data-crop-type=\"\" style=\"&#10;        --source-width: 2119;&#10;        --source-height: 1414;&#10;    \">\n        <picture><source srcset=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/400\/quality\/85\/format\/webp\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 400w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/600\/quality\/85\/format\/webp\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 600w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/800\/quality\/85\/format\/webp\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 800w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/900\/quality\/85\/format\/webp\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 900w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/1200\/quality\/85\/format\/webp\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 1200w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/1600\/quality\/85\/format\/webp\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 1600w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/1800\/quality\/85\/format\/webp\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 1800w\" data-template=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/{width}\/quality\/{quality}\/format\/{format}\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg\" sizes=\"(min-width: 1025px) 650px, calc(100vw - 30px)\" class=\"img\" type=\"image\/webp\"\/><source srcset=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/400\/quality\/85\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 400w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/600\/quality\/85\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 600w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/800\/quality\/85\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 800w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/900\/quality\/85\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 900w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/1200\/quality\/85\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 1200w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/1600\/quality\/85\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 1600w,&#10;https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/1800\/quality\/85\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg 1800w\" data-template=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2119x1414+0+0\/resize\/{width}\/quality\/{quality}\/format\/{format}\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F4f%2Fb2%2Fb9048e1f4afab8b4317d11cdb4ba%2Fgettyimages-1333447796.jpg\" sizes=\"(min-width: 1025px) 650px, calc(100vw - 30px)\" class=\"img\" type=\"image\/jpeg\"\/><\/picture>\n<\/div>\n<div class=\"credit-caption\">\n<div class=\"caption-wrap\">\n<div class=\"caption\" aria-label=\"Image caption\">\n<p>\n                A new study found the most commonly prescribed antidepressants in the U.S., called selective serotonin reuptake inhibitors, or SSRIs, tended to have fewer side effects than some older medications.<br \/>\n                <b class=\"credit\" aria-label=\"Image credit\"><\/p>\n<p>                    Guido Mieth\/Moment RF\/Getty Images<\/p>\n<p>                <\/b><br \/>\n                <b class=\"hide-caption\"><b>hide caption<\/b><\/b>\n            <\/p>\n<\/p><\/div>\n<p>            <b class=\"toggle-caption\"><b>toggle caption<\/b><\/b>\n    <\/div>\n<p>    <span class=\"credit\" aria-label=\"Image credit\"><\/p>\n<p>        Guido Mieth\/Moment RF\/Getty Images<\/p>\n<p>    <\/span>\n<\/div>\n<\/p><\/div>\n<p>Doctors have long known that antidepressants come with side effects for cardiovascular and metabolic health.<\/p>\n<p>But a major analysis from a team of researchers in the U.K. has, for the first time, pulled together data from more than 150 clinical trials to compare the physical side effects of dozens of antidepressants.<\/p>\n<p>The study,<a href=\"https:\/\/info.thelancet.com\/hubfs\/Press%20embargo\/Antidepressantsmeta.pdf\" target=\"_blank\"> published in <em>the Lancet<\/em><\/a><em> <\/em>this week, details how each medication can affect weight, blood pressure, heart rate, cholesterol and other areas of health.<\/p>\n<aside id=\"ad-backstage-wrap\" class=\"ad-wrap backstage\" aria-label=\"advertisement\">\n<\/aside>\n<div id=\"resnx-s1-5582787-100\" class=\"bucketwrap internallink insettwocolumn inset2col \">\n<div class=\"bucket img\">\n                  <a class=\"imagewrap\" id=\"featuredStackSquareImagenx-s1-5557278\" href=\"https:\/\/www.npr.org\/sections\/shots-health-news\/2025\/09\/30\/nx-s1-5557278\/ai-artificial-intelligence-mental-health-therapy-chatgpt-openai\" data-metrics-ga4=\"{&quot;category&quot;:&quot;recirculation&quot;,&quot;action&quot;:&quot;story_recirculation_click&quot;,&quot;clickType&quot;:&quot;inset box&quot;,&quot;clickUrl&quot;:&quot;https:\/\/www.npr.org\/sections\/shots-health-news\/2025\/09\/30\/nx-s1-5557278\/ai-artificial-intelligence-mental-health-therapy-chatgpt-openai&quot;}\"><picture><source srcset=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2160x2160+840+0\/resize\/100\/quality\/85\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F24%2Fab%2Fb29fb4154393bb4d06b197b69df7%2Faitherapist5.jpg\" data-original=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2160x2160+840+0\/resize\/100\/quality\/100\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F24%2Fab%2Fb29fb4154393bb4d06b197b69df7%2Faitherapist5.jpg\" data-template=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2160x2160+840+0\/resize\/{width}\/quality\/{quality}\/format\/{format}\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F24%2Fab%2Fb29fb4154393bb4d06b197b69df7%2Faitherapist5.jpg\" data-format=\"webp\" class=\"img lazyOnLoad\" type=\"image\/webp\"\/><source srcset=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2160x2160+840+0\/resize\/100\/quality\/85\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F24%2Fab%2Fb29fb4154393bb4d06b197b69df7%2Faitherapist5.jpg\" data-original=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2160x2160+840+0\/resize\/100\/quality\/100\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F24%2Fab%2Fb29fb4154393bb4d06b197b69df7%2Faitherapist5.jpg\" data-template=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2160x2160+840+0\/resize\/{width}\/quality\/{quality}\/format\/{format}\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F24%2Fab%2Fb29fb4154393bb4d06b197b69df7%2Faitherapist5.jpg\" data-format=\"jpeg\" class=\"img lazyOnLoad\" type=\"image\/jpeg\"\/><img decoding=\"async\" src=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2160x2160+840+0\/resize\/100\/quality\/100\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F24%2Fab%2Fb29fb4154393bb4d06b197b69df7%2Faitherapist5.jpg\" data-template=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/2160x2160+840+0\/resize\/{width}\/quality\/{quality}\/format\/{format}\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F24%2Fab%2Fb29fb4154393bb4d06b197b69df7%2Faitherapist5.jpg\" data-format=\"jpeg\" class=\"img lazyOnLoad\" alt=\"With therapy hard to get, people lean on AI for mental health. What are the risks?\" loading=\"lazy\"\/><\/picture><\/a>         <\/p>\n<p><!-- END CLASS=\"BUCKETBLOCK\" -->\n      <\/div>\n<p><!-- END CLASS=\"BUCKET IMG\" -->\n   <\/div>\n<p><!-- END ID=\"RESNX-S1-5582787-100\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>The end result is something akin to a &#8220;sports league table&#8221; for 30 different antidepressants based on their side effect profile, says lead author <a href=\"https:\/\/www.kcl.ac.uk\/people\/toby-pillinger\" target=\"_blank\">Dr. Toby Pillinger<\/a>, a psychiatrist at King&#8217;s College London.<\/p>\n<p>&#8220;It&#8217;s never been done at this scale before and no one&#8217;s ever put specific numbers to the amount of weight you&#8217;ll put on, or to the amount that your cholesterol goes up,&#8221; he says.<\/p>\n<p>The findings are based on existing data, mostly from 8-week drug studies, that altogether represent more than 58,000 patients.<\/p>\n<p>The most frequently prescribed antidepressants in the U.S. \u2014 <a href=\"https:\/\/www.npr.org\/2025\/09\/02\/nx-s1-5504044\/ssri-antidepressant-withdrawal-side-effects\" target=\"_blank\">selective serotonin reuptake inhibitors<\/a>, or <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/depression\/in-depth\/ssris\/art-20044825\" target=\"_blank\">SSRIs, like Zoloft and Prozac <\/a>\u2014 tended to have fewer physical side effects, according to the analysis.<\/p>\n<p>Other medications, particularly some of the older drugs, were shown to have more significant impacts.<\/p>\n<p>For example, a person who took nortriptyline, <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/depression\/in-depth\/antidepressants\/art-20046983\" target=\"_blank\">a tricyclic antidepressant<\/a>, could, on average, have an increase in heart rate that was 20 beats higher than the SSRI fluvoxamine. For other medications, the expected weight change could be 4 pounds gained, or lost.<\/p>\n<p>Pillinger says the intention is not to single out certain antidepressants as better than others.<\/p>\n<p>&#8220;It may be that one medication which is pretty bad for one person actually is pretty good for another one. I think that is the message, rather than naming and shaming certain drugs,&#8221; he says.<\/p>\n<aside id=\"ad-secondary-wrap\" class=\"ad-wrap secondary\" aria-label=\"advertisement\">\n<\/aside>\n<p>Pillinger hopes the data can help prescribers and their patients make individualized decisions about the best medication.<\/p>\n<p>In fact, he and his colleagues have created<a href=\"https:\/\/www.psymatik.com\/\" target=\"_blank\"> a free digital tool <\/a>that&#8217;s already being used by clinicians all over the world to create a &#8220;menu&#8221; of options, based on a patient&#8217;s underlying health and what side effects they&#8217;d most like to avoid.<\/p>\n<p><a href=\"https:\/\/medicine.osu.edu\/departments\/psychiatry-and-behavioral-health\/education\/research-residency-track\/faculty\" target=\"_blank\">Dr. Nina Kraguljac<\/a>, a professor at the Ohio State University, who was not involved in the research, says the study was well-done \u2014 and largely reassuring.<\/p>\n<div id=\"resnx-s1-5582787-101\" class=\"bucketwrap internallink insettwocolumn inset2col \">\n<div class=\"bucket img\">\n                  <a class=\"imagewrap\" id=\"featuredStackSquareImage1200223456\" href=\"https:\/\/www.npr.org\/sections\/health-shots\/2023\/09\/19\/1200223456\/depression-anxiety-prevention-mental-health-healthy-habits\" data-metrics-ga4=\"{&quot;category&quot;:&quot;recirculation&quot;,&quot;action&quot;:&quot;story_recirculation_click&quot;,&quot;clickType&quot;:&quot;inset box&quot;,&quot;clickUrl&quot;:&quot;https:\/\/www.npr.org\/sections\/health-shots\/2023\/09\/19\/1200223456\/depression-anxiety-prevention-mental-health-healthy-habits&quot;}\"><picture><source srcset=\"https:\/\/media.npr.org\/assets\/img\/2023\/09\/18\/gettyimages-1463841186_sq-344b3e5e35f9f56c35ada21f2c10448d73a61fe9.jpg?s=100&amp;c=85&amp;f=jpeg\" data-original=\"https:\/\/media.npr.org\/assets\/img\/2023\/09\/18\/gettyimages-1463841186_sq-344b3e5e35f9f56c35ada21f2c10448d73a61fe9.jpg?s=100&amp;c=100&amp;f=jpeg\" data-template=\"https:\/\/media.npr.org\/assets\/img\/2023\/09\/18\/gettyimages-1463841186_sq-344b3e5e35f9f56c35ada21f2c10448d73a61fe9.jpg?s={width}&amp;c={quality}&amp;f={format}\" data-format=\"webp\" class=\"img lazyOnLoad\" type=\"image\/webp\"\/><source srcset=\"https:\/\/media.npr.org\/assets\/img\/2023\/09\/18\/gettyimages-1463841186_sq-344b3e5e35f9f56c35ada21f2c10448d73a61fe9.jpg?s=100&amp;c=85&amp;f=jpeg\" data-original=\"https:\/\/media.npr.org\/assets\/img\/2023\/09\/18\/gettyimages-1463841186_sq-344b3e5e35f9f56c35ada21f2c10448d73a61fe9.jpg?s=100&amp;c=100&amp;f=jpeg\" data-template=\"https:\/\/media.npr.org\/assets\/img\/2023\/09\/18\/gettyimages-1463841186_sq-344b3e5e35f9f56c35ada21f2c10448d73a61fe9.jpg?s={width}&amp;c={quality}&amp;f={format}\" data-format=\"jpeg\" class=\"img lazyOnLoad\" type=\"image\/jpeg\"\/><img decoding=\"async\" src=\"https:\/\/media.npr.org\/assets\/img\/2023\/09\/18\/gettyimages-1463841186_sq-344b3e5e35f9f56c35ada21f2c10448d73a61fe9.jpg?s=100&amp;c=100&amp;f=jpeg\" data-template=\"https:\/\/media.npr.org\/assets\/img\/2023\/09\/18\/gettyimages-1463841186_sq-344b3e5e35f9f56c35ada21f2c10448d73a61fe9.jpg?s={width}&amp;c={quality}&amp;f={format}\" data-format=\"jpeg\" class=\"img lazyOnLoad\" alt=\"These habits can cut the risk of depression in half, a new study finds\" loading=\"lazy\"\/><\/picture><\/a>         <\/p>\n<p><!-- END CLASS=\"BUCKETBLOCK\" -->\n      <\/div>\n<p><!-- END CLASS=\"BUCKET IMG\" -->\n   <\/div>\n<p><!-- END ID=\"RESNX-S1-5582787-101\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>&#8220;What surprised me about this study is that side effects are not that severe,&#8221; says Kraguljac, who is also chair of the American Psychiatric Association&#8217;s Council on Research.<\/p>\n<p>However, she stresses that &#8220;side effects alone should not guide a clinical decision,&#8221; since the study&#8217;s results ultimately reflect an average, not the individual patient.<\/p>\n<p>&#8220;Side effects do not happen in every patient and are not necessarily a reason to deter people from taking the medications,&#8221; she says.<\/p>\n<p>The study does have some notable limitations.<\/p>\n<p>Even though many people take these drugs for months or years, the data was largely from 8-week randomized controlled trials, which are the most common.<\/p>\n<p>And some prominent side effects \u2014 that cause some people to stop taking antidepressants \u2014 were not evaluated, says <a href=\"https:\/\/www.columbiapsychiatry.org\/profile\/david-j-hellerstein-md\" target=\"_blank\">Dr. David Hellerstein<\/a>, a professor of psychiatry at Columbia University.<\/p>\n<p>He points out the impact on sexual function, gastrointestinal issues and &#8220;emotional blunting&#8221; \u2014 a sense that feelings are being muted \u2014 are all common complaints that weren&#8217;t looked at.<\/p>\n<div id=\"resnx-s1-5582787-102\" class=\"bucketwrap internallink insettwocolumn inset2col \">\n<div class=\"bucket img\">\n                  <a class=\"imagewrap\" id=\"featuredStackSquareImagenx-s1-5581409\" href=\"https:\/\/www.npr.org\/2025\/10\/22\/nx-s1-5581409\/mental-exercise-reverse-brain-change-aging-acetylcholine\" data-metrics-ga4=\"{&quot;category&quot;:&quot;recirculation&quot;,&quot;action&quot;:&quot;story_recirculation_click&quot;,&quot;clickType&quot;:&quot;inset box&quot;,&quot;clickUrl&quot;:&quot;https:\/\/www.npr.org\/2025\/10\/22\/nx-s1-5581409\/mental-exercise-reverse-brain-change-aging-acetylcholine&quot;}\"><picture><source srcset=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/4250x4250+625+0\/resize\/100\/quality\/85\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F83%2F30%2F255a3f44486285868f2e26a34c97%2Fgettyimages-488572063.jpg\" data-original=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/4250x4250+625+0\/resize\/100\/quality\/100\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F83%2F30%2F255a3f44486285868f2e26a34c97%2Fgettyimages-488572063.jpg\" data-template=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/4250x4250+625+0\/resize\/{width}\/quality\/{quality}\/format\/{format}\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F83%2F30%2F255a3f44486285868f2e26a34c97%2Fgettyimages-488572063.jpg\" data-format=\"webp\" class=\"img lazyOnLoad\" type=\"image\/webp\"\/><source srcset=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/4250x4250+625+0\/resize\/100\/quality\/85\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F83%2F30%2F255a3f44486285868f2e26a34c97%2Fgettyimages-488572063.jpg\" data-original=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/4250x4250+625+0\/resize\/100\/quality\/100\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F83%2F30%2F255a3f44486285868f2e26a34c97%2Fgettyimages-488572063.jpg\" data-template=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/4250x4250+625+0\/resize\/{width}\/quality\/{quality}\/format\/{format}\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F83%2F30%2F255a3f44486285868f2e26a34c97%2Fgettyimages-488572063.jpg\" data-format=\"jpeg\" class=\"img lazyOnLoad\" type=\"image\/jpeg\"\/><img decoding=\"async\" src=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/4250x4250+625+0\/resize\/100\/quality\/100\/format\/jpeg\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F83%2F30%2F255a3f44486285868f2e26a34c97%2Fgettyimages-488572063.jpg\" data-template=\"https:\/\/npr.brightspotcdn.com\/dims3\/default\/strip\/false\/crop\/4250x4250+625+0\/resize\/{width}\/quality\/{quality}\/format\/{format}\/?url=http%3A%2F%2Fnpr-brightspot.s3.amazonaws.com%2F83%2F30%2F255a3f44486285868f2e26a34c97%2Fgettyimages-488572063.jpg\" data-format=\"jpeg\" class=\"img lazyOnLoad\" alt=\"This image shows a cartoon-like pink brain with thin arms and legs walking on a treadmill. The brain is wearing a lime-green headband, and droplets of sweat drip out of the brain.\" loading=\"lazy\"\/><\/picture><\/a>         <\/p>\n<p><!-- END CLASS=\"BUCKETBLOCK\" -->\n      <\/div>\n<p><!-- END CLASS=\"BUCKET IMG\" -->\n   <\/div>\n<p><!-- END ID=\"RESNX-S1-5582787-102\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>Most of the side effects detailed in the study are already well-known, although he believes the work will still be &#8220;a useful touchstone&#8221; for patients and prescribers.<\/p>\n<p>&#8220;Big picture, most of these drugs seem quite safe on a lot of physical parameters, especially the newer drugs, like the SSRIs and SNRIs (serotonin-norepinephrine reuptake inhibitors),&#8221; he says.<\/p>\n<p>But for some groups of people, the side effects might be significant, he cautions, &#8220;and could affect what medicine the doctor would choose or what medicine a patient would prefer.&#8221;<\/p>\n<aside id=\"ad-third-wrap\" class=\"ad-wrap third\" aria-label=\"advertisement\">\n<\/aside>\n<p>And, he notes, side effects aren&#8217;t always a downside.<\/p>\n<p>Hellerstein has a patient who had lost a significant amount of weight due to depression, meaning an antidepressant that also led to some extra weight would actually be &#8220;healthy.&#8221;<\/p>\n<p>&#8220;I would say that is not a side effect. That is a benefit of treatment,&#8221; he says.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>A new study found the most commonly prescribed antidepressants in the U.S., called selective serotonin reuptake inhibitors, or SSRIs, tended to have fewer side effects than some older medications. Guido Mieth\/Moment RF\/Getty Images hide caption toggle caption Guido Mieth\/Moment RF\/Getty Images Doctors have long known that antidepressants come with side effects for cardiovascular and metabolic [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4865,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[327],"tags":[1837,1839,364,1099,411,919,1838],"class_list":{"0":"post-4864","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-antidepressant","9":"tag-depending","10":"tag-drug","11":"tag-effects","12":"tag-shots","13":"tag-side","14":"tag-vary"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.0 (Yoast SEO v26.0) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Antidepressant side effects vary depending on the drug : Shots - Well Rooted Wellness<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/wrwofficial.com\/index.php\/2025\/10\/23\/antidepressant-side-effects-vary-depending-on-the-drug-shots\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Antidepressant side effects vary depending on the drug : Shots\" \/>\n<meta property=\"og:description\" content=\"A new study found the most commonly prescribed antidepressants in the U.S., called selective serotonin reuptake inhibitors, or SSRIs, tended to have fewer side effects than some older medications. 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